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Dog philtrum bleeding

Nasal Planum: Common Skin Diseases Affecting the of Dog

It has been identified in large breed dogs such as Saint bernard, giant chsnauzer, and great dane. It affects the large arteries and arterioles of the central aspect of the nasal philtrum. Lesions are solitary circumscribed erosions and ulcers. Lesions often bleed and bleeding may be profuse Dermal arteritis of the nasal philtrum: surgery as an alternative to long-term medical therapy in two dogs. Pratschke KM 1, Hill PB. That helps encourage owners who aren't keen on the idea of biopsies that surgical intervention is a good way forward Dermal arteritis of the nasal philtrum (DANP) is a cutaneous vascular condition that selectively targets large vessels of the nasal philtrum of dogs; little information is published about this disease According to the Veterinary Surgery Small Animal Textbook, in order to correct the issue, the puppy's philtrum, nasal planum and oronasal barrier need to be reestablished. Left untreated, severe cleft palates may cause in puppies difficulty nursing, aspiration pneumonia, regurgitation, and malnutrition The philtrum is the vertical groove between the base of the nose and the border of a dog's upper lip, and it has a purpose. Every time a dog licks his lips, a bit of saliva stays in this groove and is drawn upwards due to capillary action. This keeps the dog's nose moist, if not wet, which enables the dog to capture scent particles from the.

Nasal arteritis in dogs is a moderate to severe inflammation of the nasal area. The artery walls are affected, causing bleeding, which can often be severe. It is also characterized by a raw and reddened inflammation on the nasal planum. Symptoms of Nasal Arteritis in Dogs My dog has what looks like a split open lip. I really don't know how/when he got it (though he did go after a possum last night for about 5 seconds before I was able to call him off. I don't know if it happened then or prior. It doesn't seem to be bleeding, just split open. I am concerned about it getting infected, because he is on prednisone. Inflammation of the arteries of the nasal philtrum (very front of nose, above upper lip

1. Make sure there is no major bleeding. If there is bleeding, have an assistant manage the bleeding (see below) while you perform CPR. 2. If possible, lay the dog on his right side. 3. Feel for a heartbeat or femoral pulse. The femoral pulse is located inside the leg in the groin region. Dogs do not have a readily palpable carotid (neck) pulse. 4 Halitosis is caused by bacteria, plaque, and tartar. Once halitosis occurs, professional veterinary oral prevention, assessment, and treatment is needed. Teeth affected by advanced periodontal disease need to be extracted. Reducing the accumulation of plaque, tartar, and resulting halitosis can be achieved by using VOHC accepted products There may be times when a piece of twig or a rock can become lodged across the roof of your dog's mouth, called the hard palate. This type of situation will cause distress to your dog and they may become panicked, clawing at their mouth or coughing

Dogs who go hiking or hunting with owners may be exposed to tick-borne illnesses, foreign bodies or rodenticides that affect nasal passages and cause bleeding. A thorough medical history and complete physical exam — from eyes to rear end — can help veterinarians determine a not-so-obvious underlying cause Dermal Arteritis Dermal arteritis of the nasal philtrum is a rare condition most commonly seen in Saint Ber-nards and characterized by a distinct linear or circular ulcer on the central portion of the nasal planum along the philtrum (Figure 11 In advanced cases, the nose may become ulcerated, bleed easily, or develop skin cancer. For Collie nose and similar disorders, sun avoidance is the most recommended treatment. Sunscreen can be applied to the noses of outdoor dogs within an hour of sun exposure and repeated frequently A 9-year-old, intact male German shorthair pointer dog was presented with well-demarcated deep erythematous ulcers targeting exclusively the skin of the nasal philtrum, accompanied by frequent series of haemorrhage

Nasal philtrum arteritis in dogs. This is a rare but very striking condition. Sonographic manifestations of bleeding disorders in dogs: including a case of apparent gastric purpura 30/03/2021. Generic selectors. Exact matches only. Exact matches only . Search in title IDIOPATHIC nasodigital hyperkeratosis is a condition that manifests as excessive accumulation of keratin on the dorsum of the nasal planum and/ or footpads. Brachycephalic breeds and cocker spaniels may be predisposed. The characteristic sign is thickened, dry and hard keratin accumulating in the sites mentioned small and medium sized arteries at the nasal philtrum of a dog is reported. MATERIAL AND METHODS A 6 year-old, male Saint Bernard dog was received for clinical examination, with the complaint of spontaneous and continuous bleeding of the nostrils. The clinical history outlined the presence of a nasal lesion when this patien Dermal arteritis of the nasal philtrum is a rarely reported condition commonly affecting large breed dogs

Nasal philtrum arteritis in dogs - Vet Practice Suppor

Dermal arteritis of the nasal philtrum: a retrospective

  1. ation of nasal crusting can document secondary bacterial infection. Biopsy of the nose under anesthesia can be performed for definitive diagnosis of nasal arteritis
  2. Congenital malformation of the nasal plane in the form of stenotic nares is part of the brachycephalic obstructive syndrome (BOS) and is a common finding in brachycephalic dogs, but also occurs in Persian cats
  3. Hi, I was thinking about your dog (and baby) last night and there is one possible contagious condition that could cause hair and pigment loss on the upper lip. That would be ringworm (a fungal infection called Dermatophytosis). Your vet would need to look at her lip with an ultraviolet light and possibly culture some hairs from the area to diagnosis ringworm
  4. Figure 87-7 Primary cleft palate in a dog. A, A portion of the left planum is disassociated with the remaining nasal planum, and the philtrum is incomplete. In this dog, the external nares are separated from the oral cavity by a layer of mucosal covered soft tissue
  5. Diagnosing and managing canine cutaneous vasculitis (Proceedings) Paul Bloom, DVM, DACVD, DABVP. Vasculitis is characterized by an aberrant immune response directed toward blood vessels. Histologically there is an inflammatory response involving and destroying blood vessels leading to ischemic changes (see histopathology)
  6. This condition affects dogs of any age or breed, although German shepherds are predisposed. It affects the mucocutaneous junctions (MCJs) of the nose and lips most frequently, but other MCJs can also be affected. This is a surface bacterial infection (usually S. pseudintermedius) wherein there is a standoff between the bacteria and the immune system at the MCJ

Oral Cavity. The oral cavity extends from the lips to the oropharynx, or more specifically to level of the palatine tonsils. 1 The lateral boundaries are the cheeks and the dorsal boundary is the hard palate and part of the soft palate. 1, 2 The ventral boundary is the tongue and floor of the mouth. The oral cavity encompasses the vestibule and the oral cavity proper Techniques 1 - 5. 1. TEMPLE - A very susceptible vital spot. If struck with sufficient force, it may cause unconsciousness or death. 2. NASION - This is the summit of the nose. If struck with sufficient force may cause death. 3. PHILTRUM - This is the area between the upper lip and the bottom of the nose

Two dogs were presented with dermal arteritis of the nasal philtrum associated with repeated episodes of bleeding. Described treatment for this condition consists of long-term, usually life-long medication with various combinations of immune suppressant and anti-inflammatory medication. This paper describes a novel surgical approach to the condition that induced long-term remission in both cases Two dogs were presented with dermal arteritis of the nasal philtrum associated with repeated episodes of bleeding. Described treatment for this condition consists of long-term, usually life-long medication with various combinations of immune suppressant and anti-inflammatory medication Some dogs and cats are prone to runny noses and sneezing, much like hay fever in humans. Allergic Rhinitis is an inflammation of the nasal passages caused by allergic reaction to airborne substances.T.. Both dogs remained healthy but had poor weight gain and vomited occasionally. Nasal Philtrum Arteritis: Related Saint Bernard's developed solitary, well-circumscribed, linear ulcers on the nasal philtrum, with repeated episodes of arterial bleeding Dermal arteritis of the nasal philtrum in a Giant Schnauzer and three Saint Bernard dogs Buy Article: $52.00 + tax (Refund Policy) Authors: Torres, Sheila M. F. 1; Brien, Timothy O. 2; Scott, Danny W. 3. Source: Veterinary Dermatology, Volume 13, Number 5, October 2002, pp..

I am Your Dog's Philtrum - Dog Discoverie

  1. Antineutrophil antibodies were demonstrated in 2 dogs. Splenectomy and steroid and azathioprine therapy reversed the condition. Nasal Philtrum Arteritis: A Giant Schnauzer was identified with a solitary, well-circumscribed, linear ulcer on the nasal philtrum, with repeated episodes of arterial bleeding
  2. philtrum is a rare condition in dogs of unknown etiology. The condition is characterized by a well-circumscribed deep round to linear to V shaped ulcer in the nasal philtrum. Clinically, affected dogs can have recurrent episodes of bleeding, sometimes necessitating emergency intervention. Proliferative arteritis of the nasal philtrum has no
  3. Brazilian Mastiff dogs. To the best of the author's knowledge, this is the first such report on this breed. Materials and methods Case report 1 A 4-year-old, male, Brazilian Mastiff dog was presented to a private veterinary clinic with a two-year history of a painful, linear and crusted ulcer located on the nasal philtrum

Structure, philtrum, nose - National Purebred Dog Day

  1. al area or chest, in which main organs are located. Bleeding cannot be stopped or alleviated after 10 or 15
  2. Proliferative arteritis is a rare, inherited vascular disease affecting the nasal philtrum, the vertical groove between a dog's nostrils. Large dogs such as St. Bernards, Giant Schnauzers, and Newfoundlands between three and six years of age may be predisposed to this condition, which causes ulceration and hemorrhage
  3. utes since the attack began. Then some kid drives up to me -- I am bleeding all over the ground and out of breath
  4. The type and severity of wound here is unclear, so here's some general information. Neosporin can be used on dogs, it is best to remove any hairs around the area to be treated. The wound can be cleaned with sterile saline water. Neosporin should o..
  5. Introducing Your Dog's Philtrum. Hello, it's your dog's philtrum talking! Yes, this is my actual name, but I am also more formally known as medial cleft. I am that little indentation at the top of your dog's upper lip. I may look a bit insignificant, but rest assured I am there for a reason

Nasal Arteritis in Dogs - Symptoms, Causes, Diagnosis

The most tumors of the tongue in dogs are malignant, and include melanomas, squamous cell carcinomas, and fibrosarcoma. Oral papillomatosis is a contagious disease of young dogs caused by the papillomavirus. The virus causes cauliflower-type warts to develop all over the surfaces of the oral cavity 1.1. The junction between the two halves of the upper lip or of an animal's nose. 'Superficial ulcers appear on the dorsum of the tongue, hard palate, and nasal philtrum.'. More example sentences. 'Two dogs were presented with dermal arteritis of the nasal philtrum associated with repeated episodes of bleeding.'

Lip cancer is a type of head and neck cancer that often starts with a lump on the lip that does not heal. Common risk factors for lip cancer include prolonged sun exposure, heavy alcohol intake. An ulcerative form of vasculitis has been described affecting a small number of Saint Bernard dogs limited to the philtrum of the nose (the area between the nostrils). In Greyhounds, a particularly severe form of vasculitis has been reported resulting in ulcerative skin lesions starting on the limbs and often occurring in conjunction with life. Arteritis of the nasal philtrum is described in four dogs. Two of the Saint Bernards were related. The lesions were solitary, well-circumscribed, linear ulcers that were neither pruritic nor painful. The age of the dogs at the time the owners first noticed the lesion ranged from 3 to 6 years. The ulcers had been present for 0.5-5 years before diagnosis was pursued

One indication for acupuncture could be in a post-op soft palate resection in a brachycephalic dog. By injecting B-12 at An-Shen to help calm a patient instead of writing an order for Acepromazine PRN may help prevent a chemically over sedated pet from aspirating and decrease oropharyngeal swelling by alleviating the constant panting It's a piercing that sits in the philtrum, also called the Cupid's bow.It's the little divot just above the lip. In the industry, this type of piercing is called a philtrum piercing A flat or smooth philtrum can present in persons with fetal alcohol spectrum disorders.: Superficial ulcers appear on the dorsum of the tongue, hard palate, and nasal philtrum.: Two dogs were presented with dermal arteritis of the nasal philtrum associated with repeated episodes of bleeding.: A midline groove called the philtrum divides the rhinarium into two, each half containing a nostril

First aid tips for an upper frenulum tear include: holding the outer lip against the teeth for 10 minutes to stop the bleeding. avoiding pulling the lip out to check the injury, as this can. Search this Resource. View main page. Table of Contents Browse by Speaker Browse by Categor The external ear consists of the prominent earflap or pinna (also called the auricle) and the external ear canal (also called the auditory canal or meatus). The pinna is a funnel-shaped structure that collects sound and directs it into the external ear canal. The pinna is covered by skin, and the outer or posterior aspect is covered by fur This is a real statement from one owner of our Pet Hero pet that received treatment for nose cancer. Nasal tumors are found in the nasal cavity and the paranasal sinuses and affect cats. Nasal tumors are less common in cats than in dogs, making up about 1% of tumors in cats. The most common types of nasal tumors in cats are squamous cell. Abstract Arteritis of the nasal philtrum is described in four dogs. Two of the Saint Bernards were related. The lesions were solitary, well‐circumscribed, linear ulcers that were neither pruritic nor painful. The age of the dogs at the time the owners first noticed the lesion ranged from 3 to 6 years. The ulcers had been present for 0.5-5 years before diagnosis was pursued. Three of the.

Bleeding and Skin open sore. WebMD Symptom Checker helps you find the most common medical conditions indicated by the symptoms bleeding and skin open sore including Phlebitis, Pilonidal cyst, and Abscess. There are 6 conditions associated with bleeding and skin open sore. The links below will provide you with more detailed information on these. Discoid lupus erythematosus (DLE) is a relatively common autoimmune skin disease of dogs. Autoimmune disease occurs when the immune system targets harmless cells of the body resulting in inflammation and disease. In DLE, skin disease tends to occur around the nose, but can extend to include areas around the eyes, lips and ears. × First Aid for Dogs By Ryan Llera, BSc, DVM; Ernest Ward, DVM Emergency Situations, Pet Services Emergencies come in all forms; automobile accidents, bite wounds, burns, heatstroke, poisoning, seizures, and more. For a general overview of what constitutes an emergency, and how to handle common crisis situations, see handout Emergencies in Dogs. What is first aid? First aid is.

[Full text] Successful medical and surgical treatment ofdo dogs have belly buttons - Daily Dog Discoveries

My dog has what looks like a split open lip

Bleeding, Blood or red colored urine and Discharge from penis. WebMD Symptom Checker helps you find the most common medical conditions indicated by the symptoms bleeding, blood or red colored urine and discharge from penis including Hemophilia, Medication reaction or side-effect, and Aspirin use The bleeding should stop and not start again, unless your nose is knocked or picked. The commonest indication for hysteroscopy is the investigation of abnormal uterine bleeding. Two dogs were presented with dermal arteritis of the nasal philtrum associated with repeated episodes of bleeding 4 / 18. MRSA can also lead to cellulitis, an infection of the deeper layers of skin and the tissues beneath them. Cellulitis can spread quickly over a few hours. The skin looks pink or red, like a. Abstract. Two dogs were presented with dermal arteritis of the nasal philtrum associated with repeated episodes of bleeding. Described treatment for this condition consists of long-term, usually life-long medication with various combinations of immune suppressant and anti-inflammatory medication

Skin Infections and Loss of Skin Color Disorders in Dogs

One of the most common causes of nasal bleeding in cats is something we may not consider too much. If we see our cat sneezing a lot, then we need to be considerate that there may be a foreign object in their nose.If this is the case, the cat may have sudden sneeze attacks and rub their nose repeatedly to try to get the foreign body out The age of the dogs at the time the owners first noticed the lesion ranged from 3 to 6 years. The ulcers had been present for 0.5-5 years before diagnosis was pursued. Three of the dogs experienced repeated, mild episodes of arterial bleeding from the ulcers. Two dogs also experienced a severe episode of bleeding that required surgical.

First Aid for Dogs VCA Animal Hospita

Broken bones in the nose, cheeks, jaw, forehead, or around the eyes are called facial fractures. Learn more from WebMD about symptoms, treatment, and when to seek medical attention Avulsion of the attachments of the cranial cruciate ligament (CCL) can occur in skeletally immature dogs. A case of avulsion of the tibial attachment of the CCL in a three-month-old Saint Bernard dog, along with the repair techniques and complications, is reported. 4. Coindé, Henri. Saint-bernard, 15 ans après In most dogs and cats there are no problems associated with the development of the mass. If the mucocele is a sublingual mucocele (ranula) (Figure 2), your pet may have some difficulty eating and may develop bleeding from trauma to the mucocele as he or she chews. A pharyngeal mucocele is generally totally undetectable until the oral cavity is. Columella and philtrum are the borders of the nasolabial angle. Figure 1. Gross anatomy of the nose. In the frontal view, the tear trough is the border to the medial lower lid. This ensures low risk of bleeding. The flap is rotated with minimal tension superomedially. Dog ears need a removal

Halitosis in Dogs VCA Animal Hospita

1. Make sure there is no major bleeding. If there is bleeding, have an assistant manage the bleeding (see below) while you perform CPR. 2. If possible, lay the dog on his right side. 3. Feel for a heartbeat or femoral pulse. The femoral pulse is located inside the leg in the groin region. Dogs do not have a readily palpable carotid (neck) pulse Nasal Dermatoses in Dogs. Nasal dermatoses are diseases of the skin on or near the nose. The nose itself is often referred to as the nasal planum. Some of these conditions are sometimes known as Collie nose or nasal solar dermatitis, depending on the cause. Many diseases may cause these conditions in dogs. These may affect the bridge of the. 1. Make sure there is no major bleeding. If there is bleeding, have an assistant manage the bleeding (see below) while you perform CPR. 2. If possible, lay the dog on its right side. 3. Feel for a heartbeat or femoral pulse. The femoral pulse is located inside the leg in the groin region. Dogs DO NOT have a readily palpable carotid (neck) pulse. 4 2. Keep your dog warm, as quiet as possible, and keep movement to a minimum, especially if there is possible trauma, broken limbs, or any neurological symptoms. 3. Contact your veterinary hospital, inform them of the situation and get specific first aid advice The technique is best for non-actively bleeding wounds that are less than 10 cm long when scalp hair is longer than 3 cm. Opposing strands of hair are brought together with a simple twist and are.

By fellow animal lovers and experts. No matter what kind of pet you love, this advice from veterinarians, trainers, and fellow pet owners will help you navigate healthy and happy pet ownership Once the bleeding has stopped, cleaning the wound thoroughly will help to decrease your facial wound healing time. Wash your hands with soap and hot water, then dry with a clean towel to reduce the chances of infecting your wound. Gently clean the wound with soap and cool water. Warm water on an open wound will cause it to start bleeding again

a. Clinically healthy gingiva. b. Mild gingivitis with slight reddening and swelling of the gingival margins. c. Moderate gingivitis, with gentle probing resulting in bleeding. d. Severe gingivitis, in which there is spontaneous hemorrhage and/or ulceration of the gingival margin. c. Hypodontia is defined as Facial nerve paralysis is a lack of motion of muscles innervated by motor branches of the facial or seventh cranial nerve (CN VII). II. Paralysis can be complete or partial, depending on the extent of the lesion. Lesions affecting either the facial nucleus (medulla) or individual branches of the facial nerve. II Hi! I'm the r/Legitpiercing Automod! Make sure you read the rules and sidebar before posting!!! For general questions, please make sure you leave detailed information. All troubleshooting postsrequire a CLEAR photo of the piercing (have someone else take it for you if possible), AND the information regarding the quality of the material, current aftercare process, age of the piercing, and. Frenulum Tear. The upper lip has the Superior Labial Frenulum and lower lip has the Inferior Labial Frenulum . Also referred to as a Frenum. These are folds of mucous membrane that are midline and extend from the gingiva to the lips. They can be easily torn when the mouth is hit or the lip is pulled/stretched The lingual frenulum is a fold of tissue that helps to anchor and stabilize your tongue. A variety of conditions can affect the lingual frenulum, including abnormal attachments, cold sores, or tears

Stock Photography by chormail 2 / 9 Bleeding Shoulder Injury Stock Photography by tobkatrina 10 / 2,629 Skin with chickenpox Pictures by justmeyo 3 / 3,878 Allergy test Stock Photographs by gribnick 1 / 226 Scar Stock Photography by ikophotos 11 / 999 Burn Scar Stock Photographs by Leaf 18 / 2,732 Doctors hand healing a burned skin area Williams syndrome is caused by a missing piece (deletion) of genetic material from a specific region of chromosome 7.The deleted region includes more than 25 genes. CLIP2, ELN, GTF2I, GTF2IRD1, and LIMK1 are among the genes that are typically deleted in people with Williams syndrome. Researchers have found that the loss of the ELN gene is associated with the connective tissue abnormalities and. Three dogs were kept alive by their breeder for three months; all exhibited waxing and waning superficial skin sloughing with erosions and fissures at areas of friction (axillae, groin, caudal tarsi, footpads), concave ear pinnae and mucocutaneous junctions (nasal planum, philtrum, lips, periocular area) 319. FMA. 58780. Anatomical terminology. The femoral triangle (or Scarpa's triangle) is an anatomical region of the upper third of the thigh. It is a subfascial space which appears as a triangular depression below the inguinal ligament when the thigh is flexed, abducted and laterally rotated Why is my bottom lip swollen for no reason and out of nowhere? Could trauma, injuries, pimples, cold sores, canker sores, allergic reactions or a sunburn causing it? Discover the causes of bottom lip swelling, treatments, remedies and ways to get rid of swollen lower lip

Body Parts You Probably Didn't Realize You Had. The study of the body and all its various parts and structures is referred to as anatomy, according to a 2017 research paper published in the Sultan Qaboos University Medical Journal. The Greek verb anatomein means to cut open and dissect, as Body World's History of Anatomy explained Feline calicivirus is a highly contagious virus that causes a mild to severe respiratory infection and oral disease in cats. It is especially common in shelters and breeding colonies, and often infects young cats. Most cats recover completely after a calicivirus infection, but rare strains can be especially deadly. The virus poses no threat to humans

There are general risks involved with having any surgery. These include adverse reactions to the anaesthetic, excessive bleeding, infection and the potential for blood clots. Antibiotic are given during surgery and continued after your operation to reduce the risk of infection. Medication (e.g. Fragmin or Clexane) to thin your blood is given during surgery and Continue Reading Gastrointestinal bleeding 2. Growth retardation 3. Neurocognitive impairment The nurse is admitting an infant who has severe growth deficiency and facial characteristics of indistinct philtrum, a thin upper lip, and short palpebral fissures. A 2-year-old eating a hot dog unsupervised 2. A 3-year-old playing alone in a wading pool 3. A 4. Otitis media, inflammation of the middle ear structures, is seen in small and large domestic animals, including dogs, cats, rabbits, ruminants, horses, pigs, and camelids. It can be unilateral or bilateral and can affect animals of all ages. Although typically sporadic, outbreaks are possible in herds

Oral Injuries in Dogs - Symptoms, Causes, Diagnosis

Cheiloplasty. The appearance of an unrepaired wide cleft lip can be distressing. Some parents feel anxiety, depression, guilt, or rejection. Lip surgery will significantly improve the infant's appearance and may thereby relieve parental apprehensions and enhance their acceptance of the child Partial and Total Maxillectomy Michael J. Odell and Patrick J. Gullane. The maxilla articulates with the bones of the skull base, and therefore maxillary surgery is occasionally performed to provide exposure for treatment of skull base pathology. This chapter, however, will focus on surgery for pathology that involves the maxilla primarily Noonan Syndrome. Noonan syndrome is characterized by facial features such as wide-set and droopy eyes, green or pale blue irises, low-set and rotated (backward) ears, wide-based and bulbous nose, deeply grooved philtrum, and poker-faced Laceration, tearing of the skin that results in an irregular wound. Lacerations may be caused by injury with a sharp object or by impact injury from a blunt object or force. They may occur anywhere on the body. In most cases, tissue injury is minimal, and infections are uncommon. However, sever Capillary vascular malformations may bleed after minor trauma and sometimes the bleeding can be difficult to stop despite the application of pressure. This is uncommon. This is uncommon. Complex syndromes require careful assessment, often by a team of specialists that may include a paediatric dermatologist , paediatrician, radiologist , plastic.

Pin on Yellow aesthetic

disease in dogs and cats. An ulcerative form of vasculitis has been described affecting a small number of Saint Bernard dogs limited to the philtrum of the nose (the area between the nostrils). In Greyhounds, a particularly severe form of vasculitis has been reported resulting in ulcerative skin lesions starting on the limb Plus, headphones, skincare/beauty products, and too many puppy dog kisses can also cause an issue, Pearce says. Remove the irritant, and the rest will follow. 02 of 08. Check Your Jewelry . After you've identified a problem area, the next step is to check if the jewelry is a proper fit and allows enough room for swelling, says Smith Other symptoms that may occur with a facial rash. In some cases, a facial rash may occur with symptoms related to other body systems including: Flu-like symptoms ( fatigue, fever, sore throat, headache, cough, aches and pains) Joint pain. Nerve pain. Numbness or burning in the lower legs and feet. Red or dry eyes